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Pediatric Gastroenterology, Hepatology & Nutrition ; : 144-148, 2015.
Article in English | WPRIM | ID: wpr-72728

ABSTRACT

Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The beta-catenin activated subtype accounts for 10-15% of all hepatocellular adenomas and specific magnetic resonance imaging features have been defined for different hepatocellular adenomas subtypes. The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of beta-catenin activated hepatocellular adenomas in a child. In this case, atypical diffuse steatosis was determined in the lesion. In the literature, diffuse steatosis, which is defined as a feature of the hepatocyte nuclear factor-1alpha-inactivated hepatocellular adenomas subtype, has not been previously reported in any beta-catenin activated hepatocellular adenomas case. Interlacing magnetic resonance imaging findings between subtypes show that there are still many mysteries about this topic and larger studies are warranted.


Subject(s)
Child , Humans , Adenoma , Adenoma, Liver Cell , beta Catenin , Carcinoma, Hepatocellular , Hepatocytes , Liver , Liver Neoplasms , Magnetic Resonance Imaging
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